In an interview with Moviehole.net promoting the movie's DVD release, star Alexa Vega hinted that prequel/sequel talks are still alive despite the film's limited release and lackluster box office:
"[F]rom the very, very beginning, we always talked about a prequel or a sequel to this movie. And it’s hard, because as of right now, we all want to do it, but... it didn’t really do as we hoped. And we didn’t really have a lot of support. But we’re hoping that the fans will come back, and it will be an underground cult classic that will grow, and that will eventually spark us to do either the prequel or the sequel to this film.
"The story’s not yet finished. There’s so much left... to wonder. 'Okay, what happens to GeneCo?' Or, 'How did they get here?'... there’s so many questions that still need to be answered."
Director Darren Lynn Bousman's grassroots "Repo tour" has done a lot to drum up support for the flick, and indeed, a kind of "Rocky Horror" buzz has slowly built around it since its release last year, so a limited-release or direct-to-video sequel is certainly well within the realm of possibility.